Regulating Maf1 Expression and Its Expanding Biological Functions
نویسندگان
چکیده
منابع مشابه
Regulating Maf1 Expression and Its Expanding Biological Functions
Maf1 is a nutrientand stress-sensitive global repressor of transcription by RNA polymerase (pol) III [1,2]. Its primary function in this context is to limit the synthesis of highly abundant 5S rRNA and tRNAs in response to nutrient availability and cellular stress [3]. Thus, Maf1 ensures the efficient use of metabolic resources while balancing the need for protein synthetic components during ce...
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Institute for Molecular Bioscience, University of Queensland, Queensland Bioscience Precinct, Brisbane, QLD 4072, Australia, Cambridge Institute for Medical Research, Department of Haematology, University of Cambridge, Wellcome Trust/MRC Building, Hills Road, Cambridge CB2 0XY, United Kingdom, and Photon Science, SLAC and Structural Biology, School of Medicine, Stanford University, 2575 Sand Hi...
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ژورنال
عنوان ژورنال: PLoS Genetics
سال: 2015
ISSN: 1553-7404
DOI: 10.1371/journal.pgen.1004896